The letter ‘A’ stands for acetyl, “spir” is derived from the plant known as Spiraea ulmaria (meadowsweet), which yields salicin, and “in” was a common suffix used for drugs at the time of the first stable synthesis of acetylsalicylic acid. The Ebers papyrus, an ancient Egyptian medical text, refers to willow as an anti-inflammatory or pain reliever for non-specific aches and pains. For commenting, please login or register as a user and agree to our Community Guidelines. 2018: Results expected from the ASPREE (aspirin in reducing events in the elderly) study to determine whether the potential benefits of low-dose aspirin outweigh the risks in healthy people older than 70 years of age. Some parts of the site may not work properly if you choose not to accept cookies. The drug works by inhibiting the production of body chemicals known as prostaglandins, which are necessary for blood clotting and for sensitizing nerve endings to pain. Filipendula ulmaria L. / SPIRaea ulmaria L. (Aspirin-rich healing plant) Medunika, Surucica. aspirin (n.) coined 1899 in German as a trademark name by German chemist Heinrich Dreser, from Latin Spiraea (ulmaria) "meadow-sweet," the plant in whose flowers or leaves the processed acid in the medicine is naturally found, + common chemical ending -in (see -ine (2)). The folks at Bayer came up with the name Aspirin. There is a concern that people who are allergic to aspirin might also be allergic to meadowsweet. 1830: Salicin is also found in the meadowsweet flower by Swiss pharmacist Johann Pagenstecher and later by German researcher Karl Jacob Löwig. Dawn Connelly is an award-winning features editor at the Pharmaceutical Journal. Aspirin was then patented in the United States in 1900. 2009: A meta-analysis by the ATT (antithrombotic trialists) collaboration suggests that aspirin has substantial overall benefit in secondary prevention but in primary prevention, aspirin is of uncertain net value as the reduction in occlusive events needs to be weighed against any increase in major bleeds (Lancet 2009;373:1849). DOI: 10.1211/CP.2014.20066661, Unsuitable or offensive? In 1899, ASA was first branded as Aspirin - taken from the “acetyl” derivative and its synthesis from Spiraea ulmaria (meadowsweet). From- Earth Healing series Aspirin was originally a trademark name that required a capital “A,” given by the German company Bayer to its preparation of acetylsalicylic acid. Salicylic acid is a natural product found in the bark of the willow tree and was used by the ancient Greeks and Native Americans, among others, to counter fever and pain. Citation: Clinical Pharmacist, September 2014, Vol 6, No 7, online | The species is hermaphrodite (has both male and female organs) and is pollinated by Bees, flies, beetles. In 1899, a German chemist named Felix Hoffmann, who worked for a German company called Bayer, rediscovered Gerhardt's formula. In order to make this chemical safer, a German researcher added a molecular acetyl group to meadowsweet extract and created acetylsalicylic acid. The word “aspirin” was invented as a conjuncton of the Latin “a spirea” meaning “of Spirea.” Plant prefers rich, moisture retentive loam, plenty of water, and a part shade to full sun exposure. 1899: Acetylsalicyclic acid is named Aspirin by Bayer. Despite being more famously associated with willow, this anti-inflammatory drug was named after meadowsweet’s old botanical name of Spiraea ulmaria. Aspirin was patented in1900; the name Aspirin comes from “A” in acetyl chloride, “spir” in Spiraea ulmaria (the plant the salicylic acid came from), and “in,” a familiar name ending for medicines. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5) Constit. Interestingly, the names Aspirin and Heroin were once trademarks belonging to Bayer. ... (Spiraea ulmaria), a plant rich in salicylates. The title was named “a” from acetyl, and “spir” from the spirea plant, meadowsweet (Filipendula ulmaria, also known as Spiraea ulmaria), the source of salicin. c3000 – 1500 BC: Willow is used as a medicine by ancient civilisations like the Sumerians and Egyptians. Filipendula ulmaria is a PERENNIAL growing to 1.2 m (4ft) by 0.4 m (1ft 4in) at a medium rate. Report this comment. In 1899, acetylsalicylic acid was named Aspirin by Bayer. Hoffmann made some of the formula and gave it to his father who was suffering from the pain of arthritis. It comes from the “A" in acetyl chloride, the "spir" in spiraea ulmaria (the plant they derived the salicylic acid from) and the “in” was a then familiar name ending for medicines. ine)… 1876: The first rigorous clinical trial of salicin finds that it induces remission of fever and joint inflammation in patients with rheumatism (Lancet 1876;1:383). In 1853, Gerhardt neutralized salicylic acid by buffering it with sodium (sodium salicylate) and acetyl chloride to create acetylsalicylic acid. Already in use for the 3500 years However, Hoffmann did not discover “aspirin.” Aspirin already in use for the 3500 years However, Hoffmann did not discover “aspirin.” Aspirin or acetylsalicylic acid is a derivative of salicylic acid. It is a mild, non-narcotic analgesic that’s useful in the relief of headache as well as muscle and joint aches. Meadowsweet has also been referred to as queen of the meadow, pride of the meadow, meadow-wort, meadow queen, lady of the meadow, dollof, meadsweet, and bridewort. The father of modern medicine was Hippocrates, who lived sometime between 460 B.C and 377 B.C. A practical guide to the use of pharmacokinetic principles in clinical practice. Aspirin allergy: Meadowsweet contains chemicals that are similar to the chemicals in aspirin. 1998 ; 351 ; 1755 ) pharmacist Johann Pagenstecher and later by researchers. And is not frost tender of non-fatal major bleeds was twice as common ( Lancet 1998 ; 351 ; )... Hardy to zone ( UK ) 2 and is pollinated by Bees, flies, beetles name.... Asthma: meadowsweet can cause lung spasms, so there is a that. Risk of initial vascular events ) study a stone tablet of medical text from the pain arthritis! To simplify and improve your experience of this website ) were also used an. From which the drug aspirin can be synthesised text from the Third of. 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